Treatment with rituximab in patients with polyneuropathy with anti-MAG antibodies. - Université de Bourgogne Accéder directement au contenu
Article Dans Une Revue Journal of Neurology Année : 2011

Treatment with rituximab in patients with polyneuropathy with anti-MAG antibodies.

Résumé

We report on a series of six patients diagnosed as anti-MAG polyneuropathy treated with rituximab. Nine months after the infusion of rituximab, sensory deficiency considered through the INCAT sensory score was improved in 5 patients and functional disability quantified by the overall neuropathy limitation scale was improved in 3 patients. Titers of anti-MAG antibodies and of monoclonal IgM gammapathy decreased respectively by 43% and 31%. No serious adverse event was observed. We did not find any predictive factors statistically related with the response to treatment.

Domaines

Neurosciences
Fichier principal
Vignette du fichier
Rituximab_revisionV4.pdf (189.56 Ko) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...

Dates et versions

hal-00703179 , version 1 (01-06-2012)

Identifiants

Citer

Emilien Delmont, P. Y. Jeandel, C. Benaïm, Eric Rosenthal, J. G. Fuzibet, et al.. Treatment with rituximab in patients with polyneuropathy with anti-MAG antibodies.. Journal of Neurology, 2011, 258 (9), pp.1717-9. ⟨10.1007/s00415-011-5994-0⟩. ⟨hal-00703179⟩
210 Consultations
482 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More