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3D analysis of the osteonal tissue in human cortical bone

Abstract : The difficulty to predict human cortical bone fragility is partly due to its complex multiscale architecture1. In particular, osteons, considered as bone structural units arise through the remodeling process that occurs at the canals surface, and are assumed to play a major role in bone mechanical properties2. If 2D data can be found in the literature, there is, however, still few 3D quantitative data regarding bone osteonal systems3. This lack of data can be explained by the difficulty to distinguish the osteon from the interstitial tissue using standard 3D imaging techniques. However, due to its sensitivity, synchrotron radiation micro-computed tomography (SR-?CT) in the quantitative phase retrieval mode was shown to be a good candidate to enhance the contrast of the osteons4. The objective of the current study was to investigate morphometric parameters of osteons in human cortical bone and their relation with osteocyte lacunae and micro-cracks using SR quantitative phase ?CT.
Keywords : OSTOENAL TISSU
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  • HAL Id : hal-02441874, version 1

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Rémy Gauthier, Hélène Follet, Cécile Olivier, David Mitton, Françoise Peyrin. 3D analysis of the osteonal tissue in human cortical bone. 25th Congress of the European Society of Biomechanics, Jul 2019, VIENNE, Austria. pp.1. ⟨hal-02441874⟩

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