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Molecular imaging in oncology drug development

Sarah R. Mudd 1, * Robert A. Comley 1 Mats Bergstrom 2 Kyle D. Holen 1 Yanping Luo 1 Sabin Carme 3 Gerard B. Fox 1 Laurent Martarello 1 John D. Beaver 1
* Auteur correspondant
1 Abbvie Inc. [North Chicago]
2 Department of Pharmaceutical Biosciences
3 ICMUB - Institut de Chimie Moléculaire de l'Université de Bourgogne [Dijon]
Abstract : Tremendous breakthroughs are being made in cancer drug discovery and development. However, such breakthroughs come at a high financial cost. At a time when there is increasing pressure on drug pricing, in part because of increased life expectancy, it is more important than ever to drive new therapeutics towards patients as efficiently as possible. In this review we discuss the applications of molecular imaging in oncology drug development, with a focus on its ability to enable better early decision making, to increase efficiency and thereby to lower costs.
Keywords : positron-emission-tomography cell lung-cancer breast-cancer early prediction tumor response pet tracer in-vitro phase-i apoptosis receptor
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Article dans une revue
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https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01561957
Contributeur : Icmub - Université de Bourgogne <>
Soumis le : jeudi 13 juillet 2017 - 13:50:04
Dernière modification le : vendredi 13 novembre 2020 - 09:08:03

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UNIV-BOURGOGNE | CNRS | INC-CNRS | ICMUB

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Sarah R. Mudd, Robert A. Comley, Mats Bergstrom, Kyle D. Holen, Yanping Luo, et al.. Molecular imaging in oncology drug development. Drug Discovery Today Biosilico, Elsevier, 2017, 22 (1), pp.140 - 147. ⟨10.1016/j.drudis.2016.09.020⟩. ⟨hal-01561957⟩

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