Anti-Mi2 dermatomyositis revisited: pure DM phenotype with muscle fiber necrosis and high risk of malignancy

Abstract : Anti-Mi2 are dermatomyositis-specific autoantibodies (Aabs) that have been associated, in small cohorts, with a good prognosis possibly related to a lower malignancy risk. Our objective was to describe the phenotype of anti-Mi-2 dermatomyositis (DM) in a larger cohort. A national multicenter retrospective cohort study was performed including all patients with a clinical phenotype suggestive of DM (cutaneous manifestations and/or muscle involvement) and a positive anti-Mi2 Aabs. Medical records were retrospectively reviewed to assess clinical and histological features, and presence of cancer occurring ± 3 years of diagnosing myositis (CAM).
Keywords : Anti-Mi2 Myositis
Type de document :
Communication dans un congrès
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https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01664160
Contributeur : Lnc - Université de Bourgogne <>
Soumis le : jeudi 14 décembre 2017 - 15:32:01
Dernière modification le : lundi 4 mars 2019 - 11:18:08

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O. Landon-Cardinal, G. Monseau, Y. Schoindre, A. Rigolet, N. Champtiaux, et al.. Anti-Mi2 dermatomyositis revisited: pure DM phenotype with muscle fiber necrosis and high risk of malignancy. 22nd International Congress of the World Muscle Society, Oct 2017, Saint Malo, France. pp.S153 ⟨10.1016/j.nmd.2017.06.218⟩. ⟨hal-01664160⟩

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