H. Blencowe, S. Cousens, M. Oestergaard, D. Chou, A. Moller et al., National, regional, and worldwide estimates of preterm birth rates Additional files Additional file 1: Supplement A. Costs and effectiveness outcomes of seven diagnostic strategies for threatened preterm labor according to the gestational age

, Scatter plots showing proportions (%) of pairs of incremental cost and incremental severe adverse neonatal events associated with CL < 15 mm or CL [16?30 mm] and fFN qualitative compared to strategy 3 and 6 according to GA. in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications, Additional file 2: Supplement B, pp.2162-72, 2012.

R. Goldenberg, J. Culhane, J. Iams, and R. Romero, Epidemiology and causes of preterm birth, The Lancet, vol.371, issue.9606, pp.75-84, 2008.
DOI : 10.1016/S0140-6736(08)60074-4

W. Nicholson, K. Frick, and N. Powe, Economic burden of hospitalizations for preterm labor in the United States, Obstet Gynecol, vol.96, pp.95-101, 2000.

P. Sagot, R. C. Rigal, E. Dantal, F. , D. Morel et al., Birth before 33 weeks gestational age. The significance of in utero-to-birth transfer in the Department of Perinatology, Rev Fr Gynecol Obstet, vol.85, pp.293-301, 1990.

L. Sanchez-ramos, I. Delke, J. Zamora, and A. Kaunitz, Fetal Fibronectin as a Short-Term Predictor of Preterm Birth in Symptomatic Patients, Obstetrics & Gynecology, vol.114, issue.3, pp.631-671, 2009.
DOI : 10.1097/AOG.0b013e3181b47217

M. Mcpheeters, W. Miller, K. Hartmann, D. Savitz, J. Kaufman et al., The epidemiology of threatened preterm labor: A prospective cohort study, American Journal of Obstetrics and Gynecology, vol.192, issue.4, pp.1325-1334, 2005.
DOI : 10.1016/j.ajog.2004.12.055

C. Sosa, F. Althabe, J. Belizan, and E. Bergel, Bed rest in singleton pregnancies for preventing preterm birth, Cochrane Database Syst Rev, vol.3, p.3581, 2015.

E. Defranco, D. Lewis, and A. Odibo, Improving the screening accuracy for preterm labor: is the combination of fetal fibronectin and cervical length in symptomatic patients a useful predictor of preterm birth? A systematic review, American Journal of Obstetrics and Gynecology, vol.208, issue.3, pp.231-237, 2013.
DOI : 10.1016/j.ajog.2012.12.015

A. Boots, L. Sanchez-ramos, D. Bowers, A. Kaunitz, J. Zamora et al., The short-term prediction of preterm birth: a systematic review and diagnostic metaanalysis, American Journal of Obstetrics and Gynecology, vol.210, issue.1, pp.54-55, 2014.
DOI : 10.1016/j.ajog.2013.09.004

M. Brik, P. Antonio, A. Perales-puchalt, V. Diago, and A. Perales, Cervical interleukin-6 as a predictive test for preterm delivery in symptomatic women: preliminary results, European Journal of Obstetrics & Gynecology and Reproductive Biology, vol.155, issue.1, pp.14-22, 2011.
DOI : 10.1016/j.ejogrb.2010.11.001

R. Goldenberg, J. Iams, A. Das, B. Mercer, P. Meis et al., The Preterm Prediction Study: Sequential cervical length and fetal fibronectin testing for the prediction of spontaneous preterm birth, American Journal of Obstetrics and Gynecology, vol.182, issue.3, pp.636-679, 2000.
DOI : 10.1067/mob.2000.104212

J. Iams, R. Goldenberg, P. Meis, B. Mercer, A. Moawad et al., The Length of the Cervix and the Risk of Spontaneous Premature Delivery, New England Journal of Medicine, vol.334, issue.9, pp.567-72, 1996.
DOI : 10.1056/NEJM199602293340904

T. Schmitz, G. Kayem, F. Maillard, M. Lebret, D. Cabrol et al., Selective use of sonographic cervical length measurement for predicting imminent preterm delivery in women with preterm labor and intact membranes, Ultrasound in Obstetrics and Gynecology, vol.101, issue.4, pp.421-427, 2008.
DOI : 10.1016/0002-9378(90)91084-P

A. Sotiriadis, S. Papatheodorou, A. Kavvadias, and G. Makrydimas, Transvaginal cervical length measurement for prediction of preterm birth in women with threatened preterm labor: a meta-analysis, Ultrasound in Obstetrics and Gynecology, vol.309, issue.1, pp.54-64, 2010.
DOI : 10.1136/bmj.309.6965.1351

R. Guidelines, Tocolysis for Women in Preterm Labour. Green?top Guideline, 2011.

A. College and G. Obstetrcian, Committee on Practice B-O: ACOG practice bulletin no. 127: Management of preterm labor, Obstet Gynecol, vol.119, pp.1308-1325, 2012.

, College National Gynécologie Obstétrique Français. La menace d'accouchement prématuré à membranes intactes, J Gynecol Obstet Biol Reprod, vol.31, pp.5-7, 2002.

L. Sentilhes, M. Senat, P. Ancel, E. Azria, G. Benoist et al., Recommandations pour la pratique clinique??: pr??vention de la pr??maturit?? spontan??e et de ses cons??quences (hors rupture des membranes)????? Texte des recommandations (texte court), Journal de Gyn??cologie Obst??trique et Biologie de la Reproduction, vol.45, issue.10, pp.1446-56, 2016.
DOI : 10.1016/j.jgyn.2016.09.011

G. Van-baaren, J. Vis, W. Grobman, P. Bossuyt, B. Opmeer et al., Cost-effectiveness analysis of cervical length measurement and fibronectin testing in women with threatened preterm labor, American Journal of Obstetrics and Gynecology, vol.209, issue.5, pp.431-439, 2013.
DOI : 10.1016/j.ajog.2013.06.029

H. Honest, C. Forbes, K. Duree, G. Norman, S. Duffy et al., Screening to prevent spontaneous preterm birth: systematic reviews of accuracy and effectiveness literature with economic modelling, Health Technology Assessment, vol.13, issue.43, pp.1-627, 2009.
DOI : 10.3310/hta13430

C. Rose, D. Mcweeney, B. Brost, N. Davies, and W. Watson, Cost-effective standardization of preterm labor evaluation, Am J Obstet Gynecol, vol.203, issue.250, pp.251-256, 2010.

S. Deshpande, A. Van-asselt, F. Tomini, N. Armstrong, A. Allen et al., Rapid fetal fibronectin testing to predict preterm birth in women

. Desplanches, 16:21 ? fast, convenient online submission ? thorough peer review by experienced researchers in your field ? rapid publication on acceptance ? support for research data, including large and complex data types ? gold Open Access which fosters wider collaboration and increased citations maximum visibility for your research: over 100M website views per year ? At BMC, research is always in progress, Cost Eff Resour Alloc, 2018.

. Learn, com/submissions Ready to submit your research ? Choose BMC and benefit from: with symptoms of premature labour: a systematic review and cost analysis, Health Technol Assess, vol.17, pp.1-138, 2013.

E. Mozurkewich, G. Naglie, M. Krahn, and R. Hayashi, Predicting preterm birth: A cost-effectiveness analysis, American Journal of Obstetrics and Gynecology, vol.182, issue.6, pp.1589-98, 2000.
DOI : 10.1067/mob.2000.106855

D. Abbott, S. Radford, P. Seed, R. Tribe, and A. Shennan, Evaluation of a quantitative fetal fibronectin test for spontaneous preterm birth in symptomatic women, American Journal of Obstetrics and Gynecology, vol.208, issue.2, pp.121-127, 2013.
DOI : 10.1016/j.ajog.2012.10.890

P. Tsiartas, R. Holst, U. Wennerholm, H. Hagberg, D. Hougaard et al., Prediction of spontaneous preterm delivery in women with threatened preterm labour: a prospective cohort study of multiple proteins in maternal serum, BJOG: An International Journal of Obstetrics & Gynaecology, vol.35, issue.12, pp.866-73, 2012.
DOI : 10.1002/uog.7457

P. Ancel, F. Goffinet, E. Group, P. Kuhn, B. Langer et al., Survival and Morbidity of Preterm Children Born at 22 Through 34 Weeks??? Gestation in France in 2011, JAMA Pediatrics, vol.169, issue.3, pp.230-238, 2015.
DOI : 10.1001/jamapediatrics.2014.3351
URL : https://hal.archives-ouvertes.fr/hal-01258705

C. Quantin, E. Benzenine, C. Ferdynus, M. Sediki, B. Auverlot et al., Advantages and limitations of using national administrative data on obstetric blood transfusions to estimate the frequency of obstetric hemorrhages, Journal of Public Health, vol.40, issue.9, pp.147-56, 2013.
DOI : 10.1016/S1701-2163(16)34656-4
URL : https://hal.archives-ouvertes.fr/hal-01194204

, Agence Technique de l'Information sur l'Hospitalisation (ATIH) http:// www.atih.sante .fr/enc-mco-donne es-2012

W. Black, The CE Plane, Medical Decision Making, vol.10, issue.3, pp.212-216, 1990.
DOI : 10.1001/jama.1986.03370060061015

M. Al, Cost-Effectiveness Acceptability Curves Revisited, PharmacoEconomics, vol.29, issue.7, pp.93-100, 2013.
DOI : 10.1111/j.1524-4733.2008.00431.x

A. Soilly, C. Lejeune, C. Quantin, S. Bejean, and J. Gouyon, Economic analysis of the costs associated with prematurity from a literature review, Public Health, vol.128, issue.1, pp.43-62, 2014.
DOI : 10.1016/j.puhe.2013.09.014
URL : https://hal.archives-ouvertes.fr/hal-01194201

G. Van-baaren, M. Peelen, E. Schuit, J. Van-der-post, B. Mol et al., Preterm birth in singleton and multiple pregnancies: evaluation of costs and perinatal outcomes, European Journal of Obstetrics & Gynecology and Reproductive Biology, vol.186, pp.34-41, 2015.
DOI : 10.1016/j.ejogrb.2014.12.024

G. Van-baaren, J. Vis, F. Wilms, M. Oudijk, A. Kwee et al., Predictive Value of Cervical Length Measurement and Fibronectin Testing in Threatened Preterm Labor, Obstetrics & Gynecology, vol.123, issue.6, pp.1185-92, 2014.
DOI : 10.1097/AOG.0000000000000229

C. Deplagne, S. Maurice-tison, F. Coatleven, F. Vandenbossche, and J. Horovitz, Utilisation s??quentielle de la longueur ??chographique du col ut??rin puis de la d??tection de la fibronectine f??tale pour pr??dire une pr??maturit?? spontan??e en cas de menace d???accouchement pr??matur??, Journal de Gyn??cologie Obst??trique et Biologie de la Reproduction, vol.39, issue.7, pp.575-83, 2010.
DOI : 10.1016/j.jgyn.2010.08.001

A. Ness, J. Visintine, E. Ricci, and V. Berghella, Does knowledge of cervical length and fetal fibronectin affect management of women with threatened preterm labor? A randomized trial, American Journal of Obstetrics and Gynecology, vol.197, issue.4, pp.426-427, 2007.
DOI : 10.1016/j.ajog.2007.07.017

T. Schmitz, F. Maillard, S. Bessard-bacquaert, G. Kayem, Y. Fulla et al., Selective use of fetal fibronectin detection after cervical length measurement to predict spontaneous preterm delivery in women with preterm labor, American Journal of Obstetrics and Gynecology, vol.194, issue.1, pp.138-181, 2006.
DOI : 10.1016/j.ajog.2005.05.074