Multiple Cold-Water Immersions Attenuate Muscle Damage but not Alter Systemic Inflammation and Muscle Function Recovery: A Parallel Randomized Controlled Trial

Angelina Freitas Siqueira (1) , Amilton Vieira (2) , Martim Bottaro (3) , João Batista Ferreira-Júnior (4) , Otávio de Toledo Nóbrega (5) , Vinícius Carolino de Souza (5) , Rita de Cássia Marqueti (6) , Nicolas Babault (7) , João Luiz Quagliotti Durigan (6)

1 Physical Education Program [University of Brasilia]
2 Physical Education Department [UDF University Center Brasília]
3 Physical Education College [University of Brasilia]
4 IF Sudeste MG - Federal Institute of Sudeste of Minas Gerais
5 Health Sciences Graduation Program [University of Brasilia]
6 Rehabilitation Sciences Graduation Program [University of Brasilia]
7 CAPS - Cognition, Action, et Plasticité Sensorimotrice [Dijon - U1093]

The aim of this study was to investigate the effects of multiple cold-water immersions (CWIs) on muscle function, markers of muscle damage, systemic inflammation and ECM degradation following exercise-induced muscle damage (EIMD). Thirty physically active males were randomly assigned to either a control (n = 15) or cold-water immersion (CWI) group (n = 15). The CWI group performed one immersion (10 degrees C for 20 min) at post-exercise and every 24 h for the following 72 h, while the control group remained in a seated position during these corresponding periods. Muscle strength, vertical jump height, muscle thickness, delayed-onset muscle soreness (DOMS), systemic creatine kinase (CK), C-reactive protein (CRP), inflammatory cytokines and matrix metalloproteinase-2 (MMP-2) activity were assessed at Pre, Post, 24, 48, 72, 96 and 168 h following EIMD. No significant time x group interaction was obtained for muscle strength, vertical jump height recovery and MMP-2 activity (p > 0.05). At 24 h, muscle thickness from the CWI group returned to baseline and was lower than the control (p = 0.04). DOMS returned to baseline at 168 h for the CWI group (p = 0.109) but not for the control (p = 0.008). At 168 h, CK showed a time-group difference with a greater peak for the control group (p = 0.016). In conclusion, multiple CWIs attenuated muscle damage, but not altered systemic inflammation and muscle function recovery.

Mots clés: regeneration; temperature; soreness; blood-flow; body cryotherapy; skeletal-muscles; matrix metalloproteinases; eccentric exercise; tissue inhibitors; physical-activity

Domaines: Neurosciences [q-bio.NC]

Angelina Freitas Siqueira, Amilton Vieira, Martim Bottaro, João Batista Ferreira-Júnior, Otávio de Toledo Nóbrega, et al.. Multiple Cold-Water Immersions Attenuate Muscle Damage but not Alter Systemic Inflammation and Muscle Function Recovery: A Parallel Randomized Controlled Trial. Scientific Reports, 2018, 8 (10961), ⟨10.1038/s41598-018-28942-5⟩. ⟨hal-01917996⟩