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Performance Evaluation and Compatibility Studies of a Compact Preclinical Scanner for Simultaneous PET/MR Imaging at 7 Tesla

Abstract : We present the design and performance of a new compact preclinical system combining positron emission tomography (PET) and magnetic resonance imaging (MRI) for simultaneous scans. The PET contains sixteen SiPM-based detector heads arranged in two octagons and covers an axial field of view (FOV) of 102.5 mm. Depth of interaction effects and detector's temperature variations are compensated by the system. The PET is integrated in a dry magnet operating at 7 T. PET and MRI characteristics were assessed complying with international standards and interferences between both subsystems during simultaneous scans were addressed. For the rat size phantom, the peak noise equivalent count rates (NECR) were 96.4 kcps at 30.2 MBq and 132.3 kcps at 28.4 MBq respectively with and without RF coil. For mouse, the peak NECR was 300.0 kcps at 34.5 MBq and 426.9 kcps at 34.3 MBq respectively with and without coil. At the axial centre of the FOV, spatial resolutions expressed as full width at half maximum / full width at tenth maximum (FWHM/FWTM) ranged from 1.69/3.19 mm to 2.39/4.87 mm. The peak absolute sensitivity obtained with a 250-750 keV energy window was 7.5% with coil and 7.9%
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https://hal-univ-bourgogne.archives-ouvertes.fr/hal-03118426
Contributeur : Alan Courteau <>
Soumis le : vendredi 22 janvier 2021 - 11:18:17
Dernière modification le : vendredi 5 février 2021 - 03:17:39
Archivage à long terme le : : vendredi 23 avril 2021 - 19:01:28

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Alan Courteau, John Mcgrath, Paul Walker, Rosie Pegg, Gary Martin, et al.. Performance Evaluation and Compatibility Studies of a Compact Preclinical Scanner for Simultaneous PET/MR Imaging at 7 Tesla. IEEE Transactions on Medical Imaging, Institute of Electrical and Electronics Engineers, 2021, 40, pp.205 - 217. ⟨10.1109/tmi.2020.3024722⟩. ⟨hal-03118426⟩

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