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Article dans une revue
Association Between Growth Differentiation Factor-15 and Heart Failure Complicating Acute Myocardial Infarction
Abstract : Background-Growth differentiation factor-15 (GDF15) is an emerging biomarker in cardiovascular diseases. We aimed to evaluate the association of GDF15 levels at admission with HF occurrence during hospitalization for acute myocardial infarction (AMI). Methods-Our prospective study included all patients admitted from June 2016 to February 2018 for type 1 AMI in the coronary care unit of the Dijon-Bourgogne University Hospital. In-hospital severe heart failure (HF) was defined as Killip class >2. Serum levels of GDF15 were obtained from blood samples were taken on admission. Results-Among the 284 AMI patients, median age was 67 years, and 27% were women. GDF15 levels were strongly correlated with age and positively correlated with most cardiovascular risk factors (hypertension and diabetes) and inflammation (CRP>3 mg/L). When compared with patients without HF (274/284), GDF15 in patients with inhospital HF (10/284) was more than two times
https://hal-univ-bourgogne.archives-ouvertes.fr/hal-03413459
Contributeur : Catherine Vergely Connectez-vous pour contacter le contributeur
Soumis le : mercredi 3 novembre 2021 - 18:02:21
Dernière modification le : jeudi 4 novembre 2021 - 03:07:40
Contributeur : Catherine Vergely Connectez-vous pour contacter le contributeur
Soumis le : mercredi 3 novembre 2021 - 18:02:21
Dernière modification le : jeudi 4 novembre 2021 - 03:07:40
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