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“Pro-youthful” factors in the “labyrinth” of cardiac rejuvenation

Abstract : The mechanisms of aging and senescence include various endogenous and exogenous factors. Among cardiovascular diseases, heart failure is a typical age-related disease. New strategies to restore cardiomyocyte cells have been reported: endogenous substances that can regenerate the heart's cardiomyocytes have been described: follistatin like 1 (FSTL1), growth-differentiation factor 11 (GDF11) and insulin-like growth factor 1 (IGF-I). Manipulation of the different anti and pro-pathways is essential to discover new approaches to regenerative therapies.
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https://hal-univ-bourgogne.archives-ouvertes.fr/hal-03433350
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Soumis le : jeudi 20 octobre 2022 - 14:40:06
Dernière modification le : vendredi 21 octobre 2022 - 03:15:09

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Luc Rochette, Catherine Vergely. “Pro-youthful” factors in the “labyrinth” of cardiac rejuvenation. Experimental Gerontology, 2016, 83, pp.1-5. ⟨10.1016/j.exger.2016.07.004⟩. ⟨hal-03433350⟩

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