Postnatal overfeeding in rats leads to moderate overweight and to cardiometabolic and oxidative alterations in adulthood

Keywords : Postnatal overfeeding heart oxidative stress Ach acetylcholine ANOVA analysis of variance AU arbitrary units BMI body mass index BK bradykinin +dP/dt left ventricular maximal pressure development −dP/dt left ventricular minimal pressure development HR heart rate IU international units L Langendorff mode LDH lactate dehydrogenase LVDP left ventricular developed pressure LVEDP left ventricular end-diastolic pressure LVESP left ventricular end-systolic pressure MMP-2 matrix metallo-proteinase-2 NF normal-fed OF overfeeding SOD superoxide dismutase RLU relative light units ROOH hydroperoxides SNP sodium nitroprussiate W working mode