Take Your PIC

Alexis Verger (1) , Didier Monté (1) , Vincent Villeret (1)

1 ERL 9002 - BSI - Biologie Structurale Intégrative

Cryo-electron microscopy has enabled unprecedented progress in the quest to reveal the structure of the whole transcription preinitiation complex. Four recent studies pave the way for a complete description of how transcription is initiated at near-atomic level.

Mots clés: cryo-EM; preinitiation complex; mediator; RNA polymerase II; transcription

Domaines: Sciences du Vivant [q-bio]

Alexis Verger, Didier Monté, Vincent Villeret. Take Your PIC. Trends in Biochemical Sciences, 2021, ⟨10.1016/j.tibs.2021.05.008⟩. ⟨hal-03281897⟩