Development of trackable metal-based drugs: new generation of therapeutic agents

Benoît Bertrand 1, 2 Pierre-Emmanuel Doulain 1 Christine Goze 1, * Ewen Bodio 1, *
* Auteur correspondant
1 ICMUB - Institut de Chimie Moléculaire de l'Université de Bourgogne [Dijon]
2 School of Chemistry, University of East Anglia
Abstract : In medicinal chemistry, the aim is not only to conceive ever more efficient molecules, but also to understand their mechanism of action. In very recent years, a new promising strategy was developed to tackle this issue: the conception of trackable therapeutic agents. Metal-based drugs are ideal to exploit this expanding area of research.
Keywords : theranostic agents phosphine-porphyrin cytotoxic properties photodynamic therapy platinum(ii) complexes organometallic compounds in-vivo cancer-cells potential anticancer agents heterocyclic carbene complexes
Type de document :
Article dans une revue
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https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01402883
Contributeur : Icmub - Université de Bourgogne <>
Soumis le : vendredi 25 novembre 2016 - 11:50:35
Dernière modification le : mercredi 20 novembre 2019 - 17:30:06

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Benoît Bertrand, Pierre-Emmanuel Doulain, Christine Goze, Ewen Bodio. Development of trackable metal-based drugs: new generation of therapeutic agents. Dalton Transactions, Royal Society of Chemistry, 2016, 45 (33), pp.13005 - 13011. ⟨10.1039/c5dt04275e⟩. ⟨hal-01402883⟩

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