The multidisciplinary management of gastro-oesophageal junction tumours: European Society of Digestive Oncology (ESDO): Expert discussion and report from the 16th ESMO World Congress on Gastrointestinal Cancer, Barcelona.

J.-L. van Laethem; F. Carneiro; M. Ducreux; H. Messman; F. Lordick; D.H. Ilson; W. Allum; K Haustermans; C. Lepage; T. Matysiak-Budnik; A Cats; W Schmiegel; A Cervantes; E van Cutsem; Ph Rougier; Th Seufferlein

doi:10.1016/j.did.2016.08.112

Article dans une revue

The multidisciplinary management of gastro-oesophageal junction tumours: European Society of Digestive Oncology (ESDO): Expert discussion and report from the 16th ESMO World Congress on Gastrointestinal Cancer, Barcelona.

J.-L. van Laethem ¹ F. Carneiro ² M. Ducreux ^{3, 4} H. Messman ⁵ F. Lordick ⁶ D.H. Ilson ⁷ W. Allum ⁸ K Haustermans ^{9, 10} C. Lepage ^{11, 12} T. Matysiak-Budnik ¹³ A Cats ¹⁴ W Schmiegel ^{15, 16} A Cervantes ^{17, 18} E van Cutsem ^{9, 10} Ph Rougier ^{19, 20} Th Seufferlein ²¹

1 Service de Gastro-Entérologie, d'Hépato-Pancréatologie et d'Oncologie Digestive - Endoscopie Digestive (hôpital Erasme)

2 Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP) and Medical Fa

3 Oncologie digestive

Département de médecine oncologique [Gustave Roussy]

4 IGR - Institut Gustave Roussy

5 Department of Internal Medicine (Klinikum Augsburg)

6 Universität Leipzig [Leipzig]

7 Memorial Sloane Kettering Cancer Center [New York]

8 Royal Marsden Hospital NHS Foundation Trust

9 KU Leuven - Catholic University of Leuven - Katholieke Universiteit Leuven

10 University Hospitals Leuven [Leuven]

11 Service d'hépato-gastroentérologie et cancérologie digestive (CHU de Dijon)

12 LNC - Lipides - Nutrition - Cancer (U866)

13 Service d'hépato-gastro-entérologie, cancérologie digestive et assistance nutritionnelle [CHU de Nantes]

14 NKI - Netherlands Cancer Institute

15 Medizinische Universitätsklinik

16 Abtlg. Gastroenterologie und Hepatologie

17 INCLIVA

18 UV - Universitat de València

19 CHU Nantes - Centre hospitalier universitaire de Nantes

20 UPD5 - Université Paris Descartes - Paris 5

21 Universität Ulm - Ulm University [Ulm, Allemagne]

Résumé : The management of GOJ cancers remains controversial and may vary between countries. Evidence-based attitudes and guidelines are not easy to elaborate since most of the trials and studies reported mixed cases of oesophageal (both adenocarcinoma and squamous cell tumours), GOJ and gastric cancers. The aim of this expert discussion and position paper is to elaborate practical recommendations that integrate evidence-reported literature and experience-based attitude covering all clinical aspects of GOJ cancer across different specialities and countries in Europe. Opinion leaders, selected on scientific merit were asked to answer to a prepared set of questions covering the approach of GOJ tumours from definition to therapeutic strategies. All answers were then discussed during a plenary session and reported here in providing a well-balanced reflection of both clinical expertise and updated evidence-based medicine. Definition, classification, diagnosis and staging of GOJ tumours were updated and debated. Therapeutic aspects including endoscopic therapy, surgical management, both multimodal curative and palliative management were also reviewed for proposing practical and consensual positions and recommendations whenever possible. GOJ tumours deserve specific attention,not only for uniformising clinical management across countries but also for performing specific clinical and translational research,mainly in the curative perioperative setting.

Keywords : Endoscopic treatment Clinical-Trial Resectable Esophageal Multimodal therapy Endoscopic Submucosal Dissection Advanced Gastric-Cancer Term Survival Differences Advanced Esophagogastric Cancer Phase-Iii Trial Gastro-oesophageal junction cancer Radiofrequency Ablation Perioperative Chemotherapy Esophageal Cancer

Type de document :

Article dans une revue

Domaine :

Sciences du Vivant [q-bio] / Médecine humaine et pathologie / Hépatologie et Gastroentérologie

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https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01430787
Contributeur : Lnc - Université de Bourgogne <>
Soumis le : mardi 10 janvier 2017 - 11:43:40
Dernière modification le : mercredi 10 juin 2020 - 10:22:05

The multidisciplinary management of gastro-oesophageal junction tumours: European Society of Digestive Oncology (ESDO): Expert discussion and report from the 16th ESMO World Congress on Gastrointestinal Cancer, Barcelona.

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The multidisciplinary management of gastro-oesophageal junction tumours: European Society of Digestive Oncology (ESDO): Expert discussion and report from the 16th ESMO World Congress on Gastrointestinal Cancer, Barcelona.

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